Posted in Digestive System, Uncategorized | By totalmed |
Drugs that target a cell surface molecule called ERBB3 could offer a more effective way to treat colon cancer, a new study suggests.
Currently, drugs that target the epidermal growth factor receptor (EGFR) are used to treat a number of cancers, but these drugs haven’t proven very effective against colon cancer. ERBB3 is closely related to EGFR. Drugs aimed at ERBB3 may be much more effective than EGFR inhibitors at treating colon cancer.
In this study, researchers genetically blocked ERBB3 in mice with colon cancer and in human colon cancer cells.
“If you genetically remove ERBB3, as you would if you were pharmacologically targeting it, then the mice rarely develop colon cancer,” lead author David Threadgill, adjunct professor in the department of genetics at the University of North Carolina at Chapel Hill and a professor in the genetics department at North Carolina State University, said in a news release.
He and his colleagues also found a dramatic increase in cell death when ERBB3 was genetically removed from human colon cancer cell lines.
“If we can use an inhibitor to block ERBB3, then it should be a very potent anti-cancer therapy,” Threadgill said.
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June 7th, 2010
Posted in Uncategorized | By totalmed | Tags: Argireline, health, skin, wrinkles
Argireline is an interesting and unique peptide that, in many tests, seems to reduce the degree and severity of wrinkles on the face, and is sometimes used as a treatment against wrinkle development. Many people consider Argireline to be a good alternative to Botox.
Facial wrinkling is common as people age. Causes are physiological pathways, formation of collagen, elastin polypeptide degradation and other problems that develop in the skin. Sort, synthetic peptides have been found in many studies to decrease the formation of facial wrinkles, and many people believe that this makes them look younger.
Argireline as an ingredient is used in cosmetic products including emulsions, gels, sera and others. The dosage recommended of Argireline is five percent or more, depending on many factors including the speed of wrinkle inhibition a person desires.
Some of the items used in wrinkle inhibition in the past have had long term health risks. That was one of the reasons for the development of Argireline. Technically speaking Argireline was identified and developed for consumer use through an analysis of skin topography using adult female volunteers. Argireline is thought by many researchers to inhibit neurotransmitter release with a potency much like other products used previously, but without the negative side effects.What exactly is Argireline? Argireline is a hexapeptide which is six naturally occurring amino acids in combination. It contains an active ingredient of acetyl hexapeptide 3 (AH3), known as a deep penetrating and powerful amino peptide. This active ingredient assists in relaxation of the intensity and frequency of contractions of facial muscles. The result of this action is sometimes referred to as a “lifting” feeling. Argireline also seems to smooth skin through detour of the degeneration of collagen and elastin. Many people, which using Argireline in cream form, use it around the yes, between the eyebrows, around the mouth and on the forehead, neck and the rest of the face. Researchers believe the results to be cumulative, and in some clinical studies a reduction in facial lines up t 17% occurred in a 15 day period, with u to 27% occurring in a 30 day period. These studies were performed with a five percent concentration of Argireline.
For more information visit: http://www.revitol.com/?aid=180563
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May 8th, 2009
Posted in Uncategorized | By totalmed | Tags: aging, antioxidants, vitamins
Just like rust on a car, oxidation can cause damage to cells and may contribute to aging.
Antioxidants help prevent oxidation, may help increase immune function and possibly decrease risk of infection and cancer. Antioxidants exist as vitamins, minerals and other compounds in foods.
A few of the better known antioxidants include carotenoids–the substance that gives fruits and vegetables their deep rich colors. Apricots, broccoli, pumpkin, cantaloupes, spinach and sweet potatoes, are some good choices in addition to lycopene in tomatoes. Vitamin C and E are also good antioxidants, as well as, magnesium, copper and zinc.
Increasing the foods you eat is the first step in getting more antioxidants. If you’re struggling, contact a registered dietitian for a nutrition check-up.
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May 8th, 2009
Posted in Uncategorized | By totalmed | Tags: diet, pills
When dieting and working out aren’t giving you the weight loss results that you want, it may be time to buy diet pills. If you’ve reached the point where you are considering adding prescription-based weight loss medications to your life, you might want to consider another option. Dietrine Carb Blocker is a great new supplement that is available without a prescription.
You may be familiar with Phase 2, which was very popular among those finding it difficult to lose weight with diet and exercise alone. Derived from the white kidney bean, Phase 2 neutralizes the enzyme alpha amylase produced in the pancreas, normally used to break down carbs. Starches are then able to pass through your digestive system without being broken down into glucose and fat, decreasing your net caloric intake, even with foods such as bread, pasta, and cereal.
By simply clicking around our website, you can safely and securely order Dietrine Carb Blocker from the comfort of your own home. And, because this is a 100 percent stimulant-free, botanical supplement, you don’t have to worry about harmful side effects or drug interactions. And, as if that wasn’t enough, when you order Dietrine Carb Blocker, we add in some great bonus material that will help you lose the weight even faster!
Free with any purchase of Dietrine Carb Blocker is a lifetime membership in our online weight loss program, which will keep you posted on new developments in the industry and provide great tips on exercise and diet programs you might want to try. We also include a weight loss hypnosis download and an e-book with 71 weight loss tips that contains all the tricks you need to promote real fat loss! With such a great supplement and a fantastic package of extras, you’ll be on your way to the body you want in no time!
For more information visit: http://www.dietrine.com/?aid=180563
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May 8th, 2009
Posted in Uncategorized | By totalmed | Tags: Chondroitin Sulfate, Glucosamine, health, nutrition, supplements
Glucosamine and chondroitin sulfate are substances found naturally in the body. Glucosamine is a form of amino sugar that is believed to play a role in cartilage formation and repair. Chondroitin sulfate is part of a large protein molecule (proteoglycan) that gives cartilage elasticity.
Both glucosamine and chondroitin sulfate are sold as dietary or nutritional supplements. They are extracted from animal tissue: glucosamine from crab, lobster or shrimp shells; and chondroitin sulfate from animal cartilage, such as tracheas or shark cartilage.
What do they do?
Past studies show that some people with mild to moderate osteoarthritis (OA) taking either glucosamine or chondroitin sulfate reported pain relief at a level similar to that of nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin and ibuprofen. Some research indicates that the supplements might also slow cartilage damage in people with OA. Definitive results about the effects of these supplements are expected from an in-depth clinical study currently being conducted by the National Institutes of Health.
For more information visit: http://www.jointadvance.com/?aid=180563
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May 8th, 2009
Posted in Uncategorized | By totalmed | Tags: calcium, cholesterol, food, magnesium, minerals
Your body only contains 4-5 teaspoons of magnesium, but it is extremely vital to every cell and your body as a whole. Magnesium works to support your bones, helps in the production of cholesterol, helps to activate many vitamins, aids in relaxing muscles, and is an essential factor in protein synthesis.About 60-65% of the magnesium in your body in contained in the bones. Your bones hold on to magnesium pretty tightly. Even when the rest of your body has a deficiency, your bones will keep most of their magnesium. Only in situations of extreme deficiency will your bones give up their magnesium. Without magnesium, your bones would becomes spongy and could not support the weight of your body.
Cholesterol cannot be synthesized without magnesium. Bile, which helps your body digest fats, cannot be produced without cholesterol. Cholesterol is also a vital component of many hormones. Aldosterone is one such hormone, and helps to control the balance of minerals, one of them being magnesium. Aldosterone needs magnesium to be produced and it also regulates magnesium’s balance. Cholesterol is also needed in the production of sex hormones, to keep your reproductive system working correctly. The stress coping hormones produced by your adrenal glands also require cholesterol for their synthesis. Cholesterol, along with lecithin and fatty acids (both require magnesium for their formation), are the main components of the myelin lining on the nerves. Myelin protects the nerves from “cross wiring”, and helps the nerve impulses to travel faster. Without adequate magnesium to produce these three lipids, your nerves can become ragged and worn out before their time. Magnesium has a calming effect on your nervous system. In fact, when taken in large enough doses, magnesium can have an anesthetizing effect.
Magnesium also has a calming effect on your muscles. Calcium stimulates the muscles to flex, and magnesium relaxes them. Without this relaxing effect, your muscles would cramp up. You may also experience muscle spasms and even convulsions, if you don’t get enough magnesium. Remember that your heart is a muscle, and the last thing you want is for it to spasm. Magnesium can prevent painful contractions at the end of pregnancy. It also helps to avoid eclampsia, which is convulsions and coma experienced by the mother after some deliveries.
Magnesium activates vitamins C and E. Therefore, if you don’t get enough magnesium, the vitamin C and E that you eat cannot be used, and your body would suffer symptoms of deficiency for those vitamins as well. Magnesium is vital to the production of parathormone, which regulates vitamin D synthesis from cholesterol compounds in your skin. The B complex also requires magnesium for their proper functioning.Amino acids are the smallest component of protein. Magnesium is needed to properly produce and combine amino acids to make the specific proteins your body needs. Many of the body’s hormones, enzymes, and tissues are made of protein. Your body has to produce a lot of each to keep your body running smoothly. The constant repair of your body requires massive amounts of protein to be produced. Without magnesium, your body could not heal itself on the outside or inside. Thousands and thousands of cells in your skin die every day. Much protein is needed to keep it looking firm and beautiful. Your blood is dependent on magnesium to supply it with new proteins, some of which help to kill infectious bacteria and viruses.
DNA is also protein. Without DNA, life would be impossible; it is the instruction book of your cells. We are constantly reproducing DNA in the replication of cells. If we could not produce DNA, we would die in a few days, if not a matter of hours. The replication of DNA allows us to have offspring. Without magnesium, we could not reproduce. Magnesium helps to digest the DNA from the cells in plant or meat foods that we eat.
For more information visit: http://www.hypercet.com/?aid=180563
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May 8th, 2009
Posted in Uncategorized | By totalmed | Tags: cigarettes, lungs, metabolism, smoking, weight gain
If you are smoking and want to make a healthy lifestyle you could start by deciding for yourself to strip off the habit from your system. But together with aiming to strip off the habit is weight gain because you will increase your appetite when you quit smoking. How can you fight this problem?
Cigarettes stimulates metabolism according to smoking cessation therapist, 250 calories in the body get burned when you consumed a pack of cigarette a day. When you quit, the body metabolism slows down resulting for those calories to slowly burn and giving you extra weight. Some people gain 2 pounds once they quit for 2 weeks and with this occurrence they tend to resume smoking to prevent weight gain so quitting will then be unsuccessful. Sticking to the decision of quitting will not be that much of a burden because eventually the metabolism will normalize. Typically, smokers only gain 5-7 pounds throughout the process of quitting. And when you think about the advantages of having a healthy and smoke free living, you will feel great inside and out and not minding those gained extra pounds.You vital organs like the lungs, heart and arteries will be free of the toxins and will start to regenerate new cells after being intoxicated with nicotine.Gradually after quitting you will notice changes in your physical appearance. Your skin is free from stress and will appeal to be fairer and smoother, those yellow stains on your fingers and fingernails will disappear, you won’t have bad breath anymore, and your teeth will be free from stains and you will have healthier gums too. These are the good fallback of quitting.
To lessen the cravings and weight gain, do drinks lots of water ideally 8oz glasses a day to keep you hydrated and to flush out toxins. Substitute healthy food with cigarette but not use junk foods because it won’t help you in becoming healthy. Don’t go for sugar rich and unhealthy foods. Do also have exercises so to keep you busy and increase metabolism. Join group therapy this will help you be encourage on the continuous quitting agenda, use also nicotine replacements. You have to have a focused mind to be able to fight challenging moments that will tempt you to go back to smoking.
For more information visit: http://www.smokedeter.com/?aid=180563
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May 8th, 2009
Posted in Uncategorized | By totalmed | Tags: digestive problems, endocrine, hypothyroidism, thyroid, Thyromine
When someone is suffering from hypothyroidism the thyroid gland is impaired, producing too little thyroid hormone. Hypothyroidism is primarily due to a dysfunction of the thyroid gland itself. If you have hypothyroidism, you can start taking control with thyromine. Act now to work towards looking better and feeling better.
Thyroid Gland and Hypothyroidism!The thyroid gland makes four hormones: Thyroxin (T4), triiodothyronine (T3), diiodothyronine (T2) and monoiodothyronine (T1). The hormones contain iodine, and the figures tell about the number of iodine atoms in each hormone molecule. T3 is not made directly, but is produced from T4. T3 is a more efficient hormone than T4. Therefore this conversion is important. The hormones produced by the thyroid gland control the body’s metabolic rate and a dysfunction to this gland can affect every organ in the body.
When the thyroid is under-active it creates a general depression of many of the cellular systems and oxidative processes in the body that are needed for energy production. This can cause the metabolic activities in the cells to decrease. Metabolic wastes can then filtrate into the organs, causing them to become sluggish. Thyroxine determines how quickly nutrients are converted into energy and how efficiently food is burned within the body.
Hypothyroidism is a condition that occurs when the thyroid gland does not produce sufficient amounts of thyroid hormones, specifically thyroxine. There are several symptoms, which can indicate a thyroid condition. The most common indicators of an under active thyroid are unexplained weight gain, moodiness, fatigue, constipation, sensitivity to cold temperatures, sudden clumsiness, fragile hair and nails and many more. An under active thyroid undermines your whole life. Thyromine can help give you your life back.
How Thyromine Works?
Thyromine ingredients consist of L-Tyrosine, Bovine Thyroid powder, Bovine Adrenal Powder, Guglipid, Nori, Piper Longum Extract and Ginger Extract. Thyromine works very well for people who have hypothyroidism. For example L-Tyrosine works to stimulate the metabolism. Guglipid works to lower bad cholesterol and increase good cholesterol. Adrenal Powder from Bovine helps regulate your body’s stress levels. Piper Longum Extract increases the production of thyroid hormones and stimulates the immune system. Finally, Ginger extract works to prevent blood clots and is used to treat digestive problems. Thyromine can make your life come together because of its combination of natural ingredients that help your thyroid to perform normally.
For more information about Thyromine, click here
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May 8th, 2009
Posted in Uncategorized | By totalmed | Tags: foot, nail fungus, nails, oxidation, toenail
Nails must be kept clean and dry always and breath fresh air. Nail fungus naturally occurs on toenail. Some reason is wearing shoes that are tied too tight, wearing shoes for a very long time can cause your feet to perspire and build fungus. Borrowing of nail cutter and other tools from other people might also cause you the transferring of fungus, because if the user has fungus infection it might get to you. Trauma can be one of the reasons for its cause. If one of your gets injured it allows the bacteria to get in.
Those people with low immune system have a great chance of getting this disease. Once it occurs in one toenail it spreads to other nails at the same feet.There are mild and aggressive kinds of medications. It can be treated in the traditional way, self treated, or it can be doctor prescribed. Most probably it is much to be preferred by doctors to guarantee the effectiveness and safeness of the treatment. Some medicines can cause side effects especially on those people who are suffering from liver diseases and can also cause allergies because of its high toxic contents. People who have depressed immune systems like those people with problem in their circulatory system, Diabetic people, elderly people and those who have HIV. Medication for nail fungus is a long-term treatment.
Awareness in preventing it can minimize its risk to preserve your healthy nail. It takes almost 3 months to be done. In three months, while your nails grow, the medicine applied prevents the fungi from growing, bringing back the healthy nail. Curing Nail fungus has its success rate at 60–80 percent and it is not assured that it will not occur again. In fact it has a 15 percent chance to reoccur.Nail Fungus is a long lasting kind of infection. That is why after treating it the doctors still recommend their patients to continue the use of anti-fungal creams. This is to prevent another build up of fungus infection.The best way to keep a healthy nail is to keep your hygiene always.
To prevent fungus infection we must follow some certain methods. The first is, wear open footwear as much as possible. Second, change socks immediately if it becomes damp or wearing absorbent socks is more preferable. Third, don’t wear high top boots if not needed. Fourth, Treat fungus as early as you can to stop its spreading.
For more information, click here
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May 8th, 2009
Posted in Uncategorized | By totalmed | Tags: blood sugar, diabetes, diabetics, hypercholesterolemia, lipids, metabolism
BERLIN—Barley beta-glucan reduces serum lipid levels, according to research presented in April at the First International Congress on Pre-Diabetes and Metabolic Syndrome. In the six-week study, 76 men and 79 women with hypercholesterolemia, aged 25 to 73, completed a four-week lowfat diet prior to baseline.
At the beginning of the trial, test subjects were randomly allocated to one of four treatment groups or a control group and assayed for blood lipids and other cardiovascular disease (CVD) biomarkers. During the course of the study, test groups were administered 3 g and 5 g doses of low molecular weight (LMW) or high molecular weight (HMW) barley beta-glucan (from Cargill) twice daily, in cereal and juice.
Posttreatment assessment of blood lipids and other CVD biomarkers revealed improvements in low-density lipoprotein (LDL) cholesterol, triglycerides, markers of glycemic control (glycosylated hemoglobin, HOMA model) and a key marker of inflammation (hs-CRP). The researchers concluded both doses of LMW and HMW barley beta-glucan improved blood lipids over a six-week treatment period.
For more information visit: http://www.optimumdiabetics.com/?aid=180563
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May 8th, 2009